Sodium-glucose co-transporter 2 (SGLT2) inhibitors, including canagliflozin, reduce the risk of cardiovascular and kidney outcomes in patients with and without type 2 diabetes, albeit with a large interindividual variation. The underlying mechanisms for this variation in response might be attributed …

The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation might be attributed to differences in angiotensin-1 …

Deze scriptie is het resultaat van onderzoek naar en ontwikkeling van de volgende vraag: ‘Hoe wordt een dataset geconstrueerd die de leefbaarheid van een gebied kan waarnemen?’. De oorsprong van deze vraag is gelegen in het bedrijf Zicht op Overheid B.V. Het bedrijf heeft de opdracht ontvangen om data …

Inhibition of the sodium−glucose cotransporter 2 (SGLT2) by canagliflozin in type 2 diabetes mellitus results in large between-patient variability in clinical response. To better understand this variability, the positron emission tomography (PET) tracer [18F]canagliflozin was developed via a Cu-mediated …

Inhibition of the sodium–glucose cotransporter 2 (SGLT2) by canagliflozin in type 2 diabetes mellitus results in large between-patient variability in clinical response. To better understand this variability, the positron emission tomography (PET) tracer [18F]canagliflozin was developed via a Cu-mediated …

Land subsidence in areas with weak soils affects a large part of the Netherlands and causes manyproblems. To solve them diverse and specialized knowledge of possible measures to prevent, mitigate or reverse land subsidence is needed. This knowledge is fragmented over many agencies, companies and individuals. …

Land subsidence in areas with weak soils affects a large part of the Netherlands and causes manyproblems. To solve them diverse and specialized knowledge of possible measures to prevent, mitigate or reverse land subsidence is needed. This knowledge is fragmented over many agencies, companies and individuals. …

With summaries in Dutch, Esperanto and English. DOI: 10.4233/uuid:d7132920-346e-47c6-b754-00dc5672b437 "The subject of this study is deformation analysis of the earth's surface (or part of it) and spatial objects on, above or below it. Such analyses are needed in many domains of society. Geodetic deformation …

KIP-project van onderzoeksprogramma Maps4Society van STW. Uit de inleiding: Dit onderzoek beschrijft "manieren, waarop deformatiemetingen worden uitgevoerd, wat deformatiemetingen, zijn en hoe ze uitgevoerd moeten worden" "Geodetische deformatieanalyse is een onderbelicht vakgebied. Slechts een beperkt …

Presentatie op Symposium 19 mei 2016