Western cities are rapidly densifying, and new building typologies are being invented to mitigate high-rise and balance residential, commercial and recreational functions. This vertical urbanization requires rethinking the traditional design of public space to promote citizens’ well-being. While the …

Young widowhood, conceptualized as the loss of one’s spouse before the age of 50, is a profoundly painful and distressing loss (Den Elzen, 2017, 2018). The literature on young widowhood shows the death of a partner generally causes a fragmentation of the self, as it violates expectations of the normal …

Aims Genetic hypertrophic cardiomyopathy (HCM) is caused by mutations in sarcomere protein-encoding genes (i.e. genotype-positive HCM). In an increasing number of patients, HCM occurs in the absence of a mutation (i.e. genotype-negative HCM). Mitochondrial dysfunction is thought to be a key driver of …

In their attempts to offer visitors meaningful experiences in historical churches, museums are increasingly experimenting with augmented reality. Arguing that an augmented reality experience should be counted as a material event in its own right, I focus on the aesthetic strategies employed in two augmented …

There is an urgent need for energy renovation of the existing building stock, in order to reach the climate goals, set in Paris in 2016. To reach climate targets, it is important to considerably lower energy demand as well as switch to fossil-free heating systems. Unfortunately, renovation rates across …

Modernisation and intensification of the agricultural land in Europe has led to habitat fragmentation. Due to habitat fragmentation, wild plant populations became small and isolated. Plant populations need to be reinforced to prevent inbreeding depression and raising them ex situ is a generally considered …

Campuses are increasingly positioning themselves as attractive locations for businesses. This research studies how this plays out in Amsterdam. We conclude that there is currently much fragmentation in efforts to position the campus landscape as business location, and provide some policy recommendations …

SMPD4 is a neutral sphingomyelinase that plays an important role in sphingolipid metabolism. Sphingolipids are a family of lipid molecules abundantly present in the brain where they play an important role in the brain development and function due to their essential cellular role as structural components …

Worldwide, fish species are the most threatened taxa among freshwater vertebrates and have declined by 76% over the past 40 years. Anthropogenic activities such as the construction of dykes and dams are the main cause of this. These obstacles are very important for contemporary society, but they pose …

Tropical deforestation is one of the main causes for habitat destruction and fragmentation for bird communities worldwide, but Costa Rica is one of the few countries where forest cover increased. Biodiversity in Costa Rica is astonishing, especially in the isolated cloud forests of the ecoregion ‘Talamancan …