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Zocht je misschien: rengers, renger?

Salivary concentrations of secretory leukocyte protease inhibitor and matrix metallopeptidase-9 following a single bout of exercise are associated with intensity and hydration status

Karen Knipping (Onderzoeker); Shirley Kartaram (Onderzoeker); Marc Teunis (Onderzoeker); Nicolaas Zuithoff (Onderzoeker); Nicole Buurman (Onderzoeker); Laura M'Rabet (Onderzoeker); Klaske van Norren (Onderzoeker); Renger Witkamp (Onderzoeker); Raymond Pieters (Lector); Johan Garssen (Onderzoeker)

Aim: To investigate the effects of exercise on salivary concentrations of inflammatory markers by analyzing a panel of 25 inflammatory markers in subjects who had participated in bicycle ergometer tests varying in workload and hydration status. Methods: Fifteen healthy young men (20-35 years) had performed …

2023GezondheidArtikel

Kinetics of Physiological Responses as a Measure of Intensity and Hydration Status During Experimental Physical Stress in Human Volunteers

Shirley Kartaram (Lid Lectoraat); Klaske van Norren; Eric Schoen; Marc Teunis (Associate Lector); Marco Mensink; Martie Verschuren; Laura M'Rabet (Onderzoeker); Isolde Besseling-van der Vaart; Karin Mohrmann; Harriët Wittink (Lector); Johan Garssen; Renger Witkamp; Raymond Pieters (Lector)

Introduction: Strenuous physical stress induces a range of physiological responses, the extent depending, among others, on the nature and severity of the exercise, a person’s training level and overall physical resilience. This principle can also be used in an experimental set-up by measuring time-dependent …

2020-09-04GezondheidArtikel

Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men

Shirley Kartaram (Lid Lectoraat); Marco Mensink; Marc Teunis (Lid Lectoraat); Eric Schoen; Lonneke Janssen - Duijghuijsen; Martie Verschuren; Karin Mohrmann; Laura M'Rabet (Lid Lectoraat); Karen Knipping; Harriët Wittink (Lector); Andy van Helvoort; Johan Garssen; Renger Witkamp; Raymond Pieters (Lector); Klaske van Norren

Background & aims Plasma citrulline concentration is considered to be a marker for enterocyte metabolic mass and to reflect its reduction as may occur during intestinal dysfunction. Strenuous exercise can act as a stressor to induce small intestinal injury. Our previous studies suggest that this comprises …

2019GezondheidArtikel

Release of major peanut allergens from their matrix under various pH and simulated saliva conditions—Ara h2 and ara h6 are readily bio-accessible

Stef J. Koppelman (Onderzoeker); Mieke Smits (Lid Lectoraat); Monic Tomassen (Onderzoeker); Govardus A.H. de de Jong (Onderzoeker); Joe Baumert (Onderzoeker); Steve L. Taylor (Onderzoeker); Renger Witkamp (Onderzoeker); Robert Jan Veldman (Lid Lectoraat); Raymond Pieters (Lector); Harry Wichers (Onderzoeker)

from the article: "Abstract: The oral mucosa is the first immune tissue that encounters allergens upon ingestion of food. We hypothesized that the bio-accessibility of allergens at this stage may be a key determinant for sensitization. Light roasted peanut flour was suspended at various pH in buffers …

2018-09-11GezondheidArtikel

N-Docosahexaenoyl Dopamine, an Endocannabinoid-like Conjugate of Dopamine and the n-3 Fatty Acid Docosahexaenoic Acid, Attenuates Lipopolysaccharide-Induced Activation of Microglia and Macrophages via COX-2

YA Wang (Onderzoeker); P. Plastina (Onderzoeker); Jean-Paul Vincken (Onderzoeker); Renate Jansen (Onderzoeker); Michiel Balvers (Onderzoeker); Jean Paul ten Klooster (Lid Lectoraat); Harry Gruppen (Onderzoeker); Renger Witkamp (Onderzoeker); Jocelijn Meijerink (Onderzoeker)

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00298 From teh publisher: "Several studies indicate that the n-3 long-chain polyunsaturated fatty acid docosahexaenoic acid (DHA) contributes to an attenuated inflammatory status in the development of neurodegenerative disorders, such as Alzheimer’s …

2017GezondheidArtikel

Docosahexaenoyl Serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23–IL-17 signalling in macrophages

Jean Paul ten Klooster (Lid Lectoraat); Raymond Pieters (Lector); Mieke Polanda; Zheng Wang; Renger Witkamp; Jocelijn Meijerink; Mark Boekschoten

Abstract from the article: "Conjugates of fatty acids and amines, including endocannabinoids, are known to play important roles as endogenous signaling molecules. Among these, the ethanolamine conjugate of the n-3 poly unsaturated long chain fatty acid (PUFA) docosahexaenoic acid (22:6n-3) (DHA) was …

2016-09-26Gezondheid; …Artikel

The effect of endurance exercise on intestinal integrity in well‐trained healthy men

Lonneke Janssen - Duijghuijsen; Marco Mensink; Kaatje Lenaerts; Ewa Fiedorowicz; Dorien van Dartel; Jurriaan Mes; Yvette Luiking; Harry Wichers; Renger Witkamp; Klaske van Norren; Shirley Kartaram (Lid Lectoraat); Anne Geijsen; Astrid van der Harst; Martie Verschuren; Leon Knippels; Raymond Pieters (Lector)

Exercise is one of the external factors associated with impairment of intestinal integrity, possibly leading to increased permeability and altered absorption. Here, we aimed to examine to what extent endurance exercise in the glycogen‐depleted state can affect intestinal permeability toward small molecules …

2016GezondheidArtikel

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