Muscle fiber-type specific expression of UCP3-protein is reported here for the firts time, using immunofluorescence microscopy

Recently, a role for uncoupling protein-3 (UCP3) in carbohydrate metabolism and in type 2 diabetes has been suggested. Mice overexpressing UCP3 in skeletal muscle showed reduced fasting plasma glucose levels, improved glucose tolerance after an oral glucose load, and reduced fasting plasma insulin levels. …

This letter to the editor argues that the assumption of a single value for the acetate recovery factor in carbon-13 stable isotope research for different individuals, can lead to significant errors in the outcomes of substrate utilization measurements.

The data of this study indicate that the acetate recovery factor, used in stable isotope research, needs to be deteremined in every subject, under similar conditions as used for the tracer-derived determination of substrate oxidation.