Clonal haematopoiesis of intermediate potential (CHIP) driven by somatic mutations in DNMT3A and TET2 has been recently recognized as a new risk factor for cardiovascular diseases (CVD). The haematopoietic clones with mutations in these genes are frequently found in myeloid malignancies and according …

The introduction of new technologies does not follow a democratic process. Yes, afterwards, when the technology is no longer new, rules and regulations will come but mainly to protect the now large lucrative companies that develop and propagate it (actually colonise us with it). It is argued that change …

Purpose: The aim of this study was to evaluate how Scheimpflug-derived parameters of eyes with Fuchs endothelial corneal dystrophy (FECD) are influenced by Descemet membrane endothelial keratoplasty (DMEK) depending on FECD severity and the presence of subclinical edema. Methods: A retrospective cohort …

Assessing the umami taste of seaweed on a chemical level can inform the use and selection of seaweed in European cuisine. Accordingly, we developed a method for the simultaneous extraction, separate clean-up and analysis of 21 free amino acids and 10 free nucleotides by reversed phase and mixed-mode …

We often judge things as being more valuable if we have to invest a considerable amount of effort instead of acquiring things effortlessly. Sometimes we can only see the value of things when we lose them. Many studies show that fast scrolling does have a disruptive effect on our understanding. On the …

The anthocyanin composition of five purple leaves cultivars of Ocimum basilicum L. was investigated by reversed-phase HPLC with mass-spectrometric detection by ESI mode with ion partial fragmentation as well as preparation of dried differently colored forms of anthocyanins encapsulated into maltodextrin …

Machine learning algorithms can help to find patterns (coherence) in the "ingredients" (data). As long as the conditions aren 't changed, taking these patterns as it 's starting point, it can extrapolate the ingredients to the (near) future, showing some future developmental possibilities (again, as …

Objectives: The aim of this study was to study measurement properties of the DutchLanguage Version of the Brief Resilience Scale (BRS-DLV) in blue and white collarworkers employed at multiple companies and to compare the validity and factorstructure to other language versions.Methods: Workers (n = 1023) …

Spatial variation in habitat riskiness has a major influence on the predator–prey space race. However, the outcome of this race can be modulated if prey shares enemies with fellow prey (i.e., another prey species). Sharing of natural enemies may result in apparent competition, and its implications for …

The chromatographic behavior of petanin, petunidin-3-O-[6-O-(4-O-(E)-para-coumaroyl-O-α-rhamnopyranosyl)-β-glucopyranoside]-5-O-β-glucopyranoside, is studied for the first time under conditions of reversed-phase high performance liquid chromatography in mobile phases with different pH values. The relationship …