Sodium-glucose co-transporter 2 (SGLT2) inhibitors, including canagliflozin, reduce the risk of cardiovascular and kidney outcomes in patients with and without type 2 diabetes, albeit with a large interindividual variation. The underlying mechanisms for this variation in response might be attributed …

The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation might be attributed to differences in angiotensin-1 …

Inhibition of the sodium−glucose cotransporter 2 (SGLT2) by canagliflozin in type 2 diabetes mellitus results in large between-patient variability in clinical response. To better understand this variability, the positron emission tomography (PET) tracer [18F]canagliflozin was developed via a Cu-mediated …

Inhibition of the sodium–glucose cotransporter 2 (SGLT2) by canagliflozin in type 2 diabetes mellitus results in large between-patient variability in clinical response. To better understand this variability, the positron emission tomography (PET) tracer [18F]canagliflozin was developed via a Cu-mediated …

Achtergrond: Van Vliet is ontwikkelaar en fabrikant van drop, pepermunt en overige zoetwaren en heeft vier eigen merken: De Bron, Meenk, Kindly’s en The Marshmallow Company. De productielocatie in Winschoten is BRC-gecertificeerd. Uit externe audits en een onverwachte klantenaudit, is naar voren gekomen …

Dit onderzoek richt zich op De Noorderbrug. Deze organisatie is gespecialiseerd in zorgverlening voor mensen met niet-aangeboren hersenletsel, doofheid met complexe problematiek, een chronische neurologische aandoening en de ziekte van Huntington. De Noorderbrug heeft geen inzicht in hoe zorgmedewerkers …

Temporary transformations of vacant buildings could alleviate the shortage of housing for urgent home seekers. However, not much is known about the transformation of buildings into temporary, adequate, and affordable housing. A multidisciplinary literature review covering design, indoor environmental …

There is a shortage of housing and people with a lower income suffer most from this. Vacant buildings are transformed to provide quick housing for them, but it is not sure whether this provides a comfortable home, both from an indoor climate and a meaning making perspective. Existing material about completed …

How to find out what students, starters, and other new households of transformed buildings need to create a home environment with a comfortable climate without losing meanings attributed to the home?

In deze managementsamenvatting wordt de inhoud van dit rapport beknopt weergegeven. Het onderwerp, alsmede de probleemstelling en het doel van dit onderzoek zullen nader worden toegelicht. Bovendien zullen de belangrijke bevindingen en conclusies, die uit dit onderzoek naar voren zijn gekomen, nader …