Clonal haematopoiesis of intermediate potential (CHIP) driven by somatic mutations in DNMT3A and TET2 has been recently recognized as a new risk factor for cardiovascular diseases (CVD). The haematopoietic clones with mutations in these genes are frequently found in myeloid malignancies and according …

When my daughter was born eleven years ago, many new worlds opened for me. In addition to the world of diapers and sleepless nights, my use and perception of public space changed. The width of the sidewalk and loose paving stones suddenly became important. First through my walks with the pram and a …

Diabetes remains a major risk for atherosclerotic-cardiovascular disease (CVD). While many mechanisms have been explored, the full extent of how diabetes promotes CVD remains unknown. An emerging area in diabetes is the influence of epigenetic regulation of gene expression. Diabetes has been shown to …

Betreffend onderzoek is uitgevoerd bij de gemeente Borsele. De aanleiding van het onderzoek vindt haar oorsprong in een toekomstige wetswijziging. De rechtmatigheidsverantwoording, welke momenteel door de accountant wordt afgegeven bij de jaarstukken, zal naar verwachting vanaf boekjaar 2022 worden afgegeven …

Empirical studies in the creative arts therapies (CATs; i.e., art therapy, dance/movement therapy, drama therapy, music therapy, psychodrama, and poetry/bibliotherapy) have grown rapidly in the last 10 years, documenting their positive impact on a wide range of psychological and physiological outcomes …

Compassionate conservation is based on the ethical position that actions taken to protect biodiversity should be guided by compassion for all sentient beings. Critics argue that there are 3 core reasons harming animals is acceptable in conservation programs: the primary purpose of conservation is biodiversity …

Ulus Baker (1960 – 2007) was a Turkish-Cypriot sociologist, philosopher, and public intellectual. He was born in Ankara, Turkey in 1960. He studied Sociology at Middle East Technical University in Ankara, where he taught as a lecturer until 2004. Baker wrote prolifically in influential Turkish journals …

Purpose For this research that specific purpose is finding ecological neighbourhoods and real estate agents who valuate residential properties in these specific locations. Determining financing valuation with suitable valuation techniques for new residential houses in ecological neighbourhoods, formulating …

This article describes a relatively straightforward procedure to knock out the gene that encodes the invertase enzyme in baker’s yeast. The SUC2 gene, which encodes for the invertase enzyme, is knocked out by a single-step PCR knock out method. The knockout is subsequently confirmed at the genetic level …

Om het mbo-onderwijs aan te laten sluiten bij de snel veranderende hedendaagse maatschappij en mbo-studenten uitdaging te bieden tijdens de lessen, is er onderzocht of een didactische werkvorm effect heeft op leerresultaat en ervaring van mbo-studenten. Er is gekeken naar de verschillen tussen verbale …