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The impact and treatment of scars after breast reconstruction: scarred for life?

Kristel Everaars (Onderzoeker)

Breast cancer is the most prevalent form of cancer that affects women worldwide, posing a significant burden on public health. While advancements in early detection and improved treatments have led to a remarkable 90% five-year survival rate and an 83% ten-year survival rate, this has also resulted in …

2024GezondheidProefschrift

Dietary Supplementation with Nondigestible Oligosaccharides Reduces Allergic Symptoms and Supports Low Dose Oral Immunotherapy in a Peanut Allergy Mouse Model

Laura Wagenaar (Onderzoeker); Marianne Bol-Schoenmakers (Onderzoeker); Giulio Giustarini (Onderzoeker); Marlotte M. Vonk (Onderzoeker); Betty C.A.M. van Esch (Onderzoeker); Léon M.J. Knippels (Onderzoeker); Johan Garssen (Onderzoeker); Joost Smit (Onderzoeker); Raymond Pieters (Lector)

Abstract 1 Scope A major downside of oral immunotherapy (OIT) for food allergy is the risk of severe side effects. Non‐digestible short‐ and long‐chain fructo‐oligosaccharides (scFOS/lcFOS) reduce allergy development in murine models. Therefore, it is hypothesized that scFOS/lcFOS can also support …

2018-08-13GezondheidArtikel

The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow's milk- and peanut allergy models

Marlotte M. Vonk (Onderzoeker); Laura Wagenaar (Onderzoeker); Raymond Pieters (Lector); Léon M.J. Knippels (Onderzoeker); L.E.M. Willemsen (Onderzoeker); J.J. Smit (Onderzoeker); BCAM van Esch (Onderzoeker); J. Garssen (Onderzoeker)

From Pubmed: " BACKGROUND: Antigen-specific immunotherapy (AIT) is a promising therapeutic approach for both cow's milk allergy (CMA) and peanut allergy (PNA), but needs optimization in terms of efficacy and safety. AIM: Compare oral immunotherapy (OIT) and subcutaneous immunotherapy (SCIT) in …

2017GezondheidArtikel

Improved Efficacy of Oral Immunotherapy Using Non-Digestible Oligosaccharides in a Murine Cow's Milk Allergy Model

Marlotte M. Vonk (Onderzoeker); Mara A.P. Diks (Onderzoeker); Laura Wagenaar (Onderzoeker); J.J. Smit (Onderzoeker); Raymond Pieters (Lector); Johan Garssen (Onderzoeker); Betty C.A.M. van Esch (Onderzoeker); Léon M.J. Knippels (Onderzoeker)

From teh UU repository: "Background: Oral immunotherapy (OIT) is a promising therapeutic approach to treat food allergic patients. However, there are some concerns regarding its safety and long-term efficacy. The use of non-digestible oligosaccharides might improve OIT efficacy since they are known to …

2017GezondheidArtikel

Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients

Friedemann Schad (Onderzoeker); Anja Thronicke (Onderzoeker); Antje Merkle (Onderzoeker); Harald Matthes (Onderzoeker); Megan L. Steele (Onderzoeker)

Background: Immune-related adverse drug reactions (ADRs) to immunotherapy agents have been associated with beneficial clinical outcomes in oncology. Viscum album L. (VA, European mistletoe) is frequently used as an immunomodulatory agent alongside conventional cancer treatment in Europe. VA has been …

2017GezondheidArtikel

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The impact and treatment of scars after breast reconstruction: scarred for life?

Dietary Supplementation with Nondigestible Oligosaccharides Reduces Allergic Symptoms and Supports Low Dose Oral Immunotherapy in a Peanut Allergy Mouse Model

The efficacy of oral and subcutaneous antigen-specific immunotherapy in murine cow's milk- and peanut allergy models

Improved Efficacy of Oral Immunotherapy Using Non-Digestible Oligosaccharides in a Murine Cow's Milk Allergy Model

Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients

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