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Effects of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity

Naaktgeboren, Willeke R.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker); Van Harten, Wim H.; Aaronson, Neil K.; Scott, Jessica M.; Sonke, Gabe; Van Der Wall, Elsken; Velthuis, Miranda; Leiner, Tim; Teske, Arco J.; May, Anne M.; Groen, Wim G.

Objective Animal data suggest that exercise during chemotherapy is cardioprotective, but clinical evidence to support this is limited. This study evaluated the effect of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity. Methods This is a follow-up study of two previously …

2023-10-30AlgemeenArtikel

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer

Groen, Wim G.; Naaktgeboren, Willeke R.; van Harten, Wim H.; van Vulpen, Jonna K.; Kool, Nathalie (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); Sonke, Gabe S.; van der Wall, Elsken; Velthuis, Miranda J.; Aaronson, Neil K.; May, Anne M.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker)

INTRODUCTION: An optimal relative dose intensity (RDI) of adjuvant chemotherapy is associated with better survival in patients with breast cancer. Little is known about the role of physical fitness in attaining an adequate RDI in patients with early stage breast cancer. We investigated the association …

2022-04AlgemeenArtikel

Moderators of exercise effects on cancer-related fatigue

van Vulpen, Jonna K; Sweegers, Maike G; Peeters, Petra H M; Courneya, Kerry S; Newton, Robert U; Aaronson, Neil K; Jacobsen, Paul B; Galvão, Daniel A; Chinapaw, Mai J; Steindorf, Karen; Irwin, Melinda L; Stuiver, Martijn M (Faculteit Gezondheid); Hayes, Sandi; Griffith, Kathleen A; Mesters, Ilse; Knoop, Hans; Goedendorp, Martine M; Mutrie, Nanette; Daley, Amanda J; McConnachie, Alex; Bohus, Martin; Thorsen, Lene; Schulz, Karl-Heinz; Short, Camille E; James, Erica L; Plotnikoff, Ronald C; Schmidt, Martina E; Ulrich, Cornelia M; van Beurden, Marc; Oldenburg, Hester S; Sonke, Gabe S; van Harten, Wim H; Schmitz, Kathryn H; Winters-Stone, Kerri M; Velthuis, Miranda J; Taaffe, Dennis R; van Mechelen, Willem; Kersten, Marie José; Nollet, Frans; Wenzel, Jennifer; Wiskemann, Joachim; Verdonck-de Leeuw, Irma M; Brug, Johannes; May, Anne M; Buffart, Laurien M

PURPOSE: Fatigue is a common and potentially disabling symptom in patients with cancer. It can often be effectively reduced by exercise. Yet, effects of exercise interventions might differ across subgroups. We conducted a meta-analysis using individual patient data of randomized controlled trials (RCTs) …

2020-02AlgemeenArtikel

Adherence to and satisfaction with low-intensity physical activity and supervised moderate-high intensity exercise during chemotherapy for breast cancer

van Waart, Hanna; Buffart, Laurien M.; Stuiver, Martijn M.; van Harten, Wim H.; Sonke, Gabe S.; Aaronson, Neil K.

PURPOSE: In this study, we investigated factors associated with program adherence and patient satisfaction with a home-based physical activity program (Onco-Move, N = 77) and a supervised exercise program with a home-based component (OnTrack, N = 76). METHODS: We assessed adherence via self-report (home-based …

2020AlgemeenArtikel

Effect of physical exercise on cognitive function and brain measures after chemotherapy in patients with breast cancer (PAM study): protocol of a randomised controlled trial

Witlox, Lenja; Schagen, Sanne B; de Ruiter, Michiel B; Geerlings, Mirjam I; Peeters, Petra H M; Koevoets, Emmie W; van der Wall, Elsken; Stuiver, Martijn (Faculteit Gezondheid); Sonke, Gabe; Velthuis, Miranda J; Palen, Job A M van der; Jobsen, Jan J; May, Anne M; Monninkhof, E M

INTRODUCTION: After treatment with chemotherapy, many patients with breast cancer experience cognitive problems. While limited interventions are available to improve cognitive functioning, physical exercise showed positive effects in healthy older adults and people with mild cognitive impairment. The …

2019-06AlgemeenArtikel

Targeting Exercise Interventions to Patients With Cancer in Need: An Individual Patient Data Meta-Analysis

Buffart, Laurien M; Sweegers, Maike G; May, Anne M; Chinapaw, Mai J; van Vulpen, Jonna K; Newton, Rob U; Galvão, Daniel A; Aaronson, Neil K; Stuiver, Martijn M (Faculteit Gezondheid); Jacobsen, Paul B; Verdonck-de Leeuw, Irma M; Steindorf, Karen; Irwin, Melinda L; Hayes, Sandi; Griffith, Kathleen A; Lucia, Alejandro; Herrero-Roman, Fernando; Mesters, Ilse; van Weert, Ellen; Knoop, Hans; Goedendorp, Martine M; Mutrie, Nanette; Daley, Amanda J; McConnachie, Alex; Bohus, Martin; Thorsen, Lene; Schulz, Karl-Heinz; Short, Camille E; James, Erica L; Plotnikoff, Ronald C; Arbane, Gill; Schmidt, Martina E; Potthoff, Karin; van Beurden, Marc; Oldenburg, Hester S; Sonke, Gabe S; van Harten, Wim H; Garrod, Rachel; Schmitz, Kathryn H; Winters-Stone, Kerri M; Velthuis, Miranda J; Taaffe, Dennis R; van Mechelen, Willem; José Kersten, Marie; Nollet, Frans; Wenzel, Jennifer; Wiskemann, Joachim; Brug, Johannes; Courneya, Kerry S

Background: Exercise effects in cancer patients often appear modest, possibly because interventions rarely target patients most in need. This study investigated the moderator effects of baseline values on the exercise outcomes of fatigue, aerobic fitness, muscle strength, quality of life (QoL), and self-reported …

2018-11AlgemeenAndersoortig materiaal

Cost–utility and cost-effectiveness of physical exercise during adjuvant chemotherapy

van Waart, Hanna; van Dongen, Johanna M.; van Harten, Wim H.; Stuiver, Martijn M. (Faculteit Gezondheid); Huijsmans, Rosalie; Hellendoorn-van Vreeswijk, Jeannette A. J. H. H.; Sonke, Gabe S.; Aaronson, Neil K

2017AlgemeenArtikel

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