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Lower birth weight is associated with alterations in dietary intake in adolescents independent of genetic factors

Doornweerd, Stieneke; IJzerman, Richard G.; Weijs, Peter J.M. (Lectoraat Voeding En Beweging); Diamant, Michaela; de Geus, Eco J.; Boomsma, Dorret I.

BACKGROUND & AIMS: Lower birth weight is associated with an increased risk of cardiovascular and metabolic disease. These associations may, at least in part, be explained by alterations in dietary intake in later life. The aim of this study is to examine whether lower birth weight is associated with …

2017-02AlgemeenArtikel

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

Linssen, Margot M L; van Raalte, Daniel H; Toonen, Erik J M; Alkema, Wynand (Data Science For Life Science & Health); van der Zon, Gerard C; Dokter, Wim H; Diamant, Michaela; Guigas, Bruno; Ouwens, D Margriet

Glucocorticoids (GCs), such as prednisolone (PRED), are widely prescribed anti-inflammatory drugs, but their use may induce glucose intolerance and diabetes. GC-induced beta cell dysfunction contributes to these diabetogenic effects through mechanisms that remain to be elucidated. In this study, we hypothesized …

2011-11-01AlgemeenArtikel

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Lower birth weight is associated with alterations in dietary intake in adolescents independent of genetic factors

Prednisolone-induced beta cell dysfunction is associated with impaired endoplasmic reticulum homeostasis in INS-1E cells

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