Samenvatting

Advances in neuroscience and the identification of the new concept of central sensitisation (CS) have increased understanding of the complexity of pain, offered explanations for pain without a source and reasons for its persistence, forcing a more holistic chronic pain (CP) treatment approach. Pain neuroscience education (PNE) and its positive effects on chronic pain have been researched and proven, but the effects on CS remain unclear. This systematic review of randomised control trials (RCTs) aims to investigate the effectiveness of PNE on CS processes in addition to pain perceptions and cognitions in individuals with CP. The results will provide evidence for guiding the treatment of chronic pain with suspected central sensitisation.