Samenvatting

Cancer was diagnosed in 19.292.789 patients worldwide in 2020, depending on the type of cancer treatment may involve chemotherapy. If a neurotoxic agent is used, patients can develop chemotherapy-induced peripheral neuropathy (CIPN) affecting 68% of patients within the first months of treatment. CIPN involves sensory, motor or autonomic symptoms. As there is currently no treatment, most often during chemotherapy the dosage needs to be reduced which may have a negative effect on the survival rate of patients. The American Society of Clinical Oncology (ASCO) only recommend the usage of duloxetine to treat painful CIPN symptoms, nonetheless studies having found positive outcomes with exercise therapy, acupuncture or whole-body vibration. As there are no recommendations made, this review is aimed to answer the question whether active interventions or passive non-pharmacological interventions are more effective in the treatment of CIPN symptoms and decreased Quality of Life in patients diagnosed with CIPN.