This article explores the challenges local youth workers face at the intersection of providing social care and detecting violent extremism. Extremism and other radical ideologies are often assumed to be a harbinger of terrorism. Even though both are still a rare phenomenon among adolescents, European …

Optimizing physical performance is a major goal in current physiology. However, basic understanding of combining high sprint and endurance performance is currently lacking. This study identifies critical determinants of combined sprint and endurance performance using multiple regression analyses of physiologic …

The research is conducted for Nissan Nederland. Since 2017, this company has changed their method of targets engagement. The goal of this change is dividing the method of targets of two car branches of Nissan Nederland, the private market versus the fleet market. The result of this change should help …

Background Geographical inequalities in perinatal health and child welfare require attention. To improve the identification, and care, of mothers and young children at risk of adverse health outcomes, the HP4All-2 program was developed. The program consists of three studies, focusing on creating a continuum …

xecutive summaryTransformation could be defined as a major change of a vacant building itself and the function of the building (Remoy, 2014). Transformation is a solution to decrease the amount of vacancy in the office market. The demand for the amount of M² office space is grown with 2,1% in relative …

RS Sailing is currently lacking sufficient monitoring the performance of their global dealers because the management system of RS Sailing did not grow along with the growth the company went through. Therefore, a structured approach to keep track on their global dealers performances is desired. The …

In the shift towards the Big Society, it is widely proclaimed that citizen participation and citizens’ initiatives are indispensable to maintaining services that used to be run by local or regional governments. Despite the increased interest in citizens’ initiatives, research has scarcely debated what …

To achieve emission reduction targets and to improve local air quality of cities, the uptake of Electric Freight Vehicles (EFV) is essential. Knowledge concerning why companies do adopt EFV is lacking. Research about the diffusion of innovations and the market of EFV shows that frontrunner companies …

Accurate assessment of TP53 gene status in sporadic tumors and in the germline of individuals at high risk of cancer due to Li–Fraumeni Syndrome (LFS) has important clinical implications for diagnosis, surveillance, and therapy. Genomic data from more than 20,000 cancer genomes provide a wealth of information …

The thesis project was devoted to a differentiation of different types of cancer cells checking the effectiveness of the novel anti-leukemia chemicals and exploring whether the best anti-leukemia targets also target bone cancers. The research question of this project is as follows: “How leukemia and …