Development of novel testing strategies to detect adverse human health effects is of interest to replace in vivo-based drug and chemical safety testing. The aim of the present study was to investigate whether physiologically based kinetic (PBK) modeling-facilitated conversion of in vitro toxicity data …

Horizontal axis wind turbines (HAWTs) experience three-dimensional rotational and unsteady aerodynamic phenomena at the rotor blades sections. These highly unsteady three-dimensional effects have a dramatic impact on the aerodynamic load distributions on the blades, in particular, when they occur at …

As every new generation of civil aircraft creates more on-wing data and fleets gradually become more connected with the ground, an increased number of opportunities can be identified for more effective Maintenance, Repair and Overhaul (MRO) operations. Data are becoming a valuable asset for aircraft …

PURPOSE: Premorbid conditions affect prognosis of acutely-ill aged patients. Several lines of evidence suggest geriatric syndromes need to be assessed but little is known on their relative effect on the 30-day survival after ICU admission. The primary aim of this study was to describe the prevalence …

BACKGROUND: Currently used performance measures for discrimination were not informative to determine the clinical benefit of predictor variables. The purpose was to evaluate if a former relevant predictor, kinesiophobia, remained clinically relevant to predict chronic occupational low back pain (LBP) …

In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A–4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and …

Deploying Learning Analytics that significantly improve learning outcomes remains a challenge. Motivation has been found to be related to academic achievement and is argued to play an essential role in efficient learning. We developed a Learning Analytics dashboard and designed an intervention that relies …

Purpose The Work Assessment Triage Tool (WATT) is a clinical decision support tool developed using machine learning to help select interventions for patients with musculoskeletal disorders. The WATT categorizes patients based on individual characteristics according to likelihood of successful return …

Dynamic stall phenomena bring risk for negative damping and instability in wind turbine blades. It is crucial to model these phenomena accurately to reduce inaccuracies in predicting design driving (fatigue) loads. Inaccuracies in current dynamic stall models may be due to the facts that they are not …

Executive summary  Smart buildings are becoming of increased importance in the Dutch office building environment, due to the new legislation of the government to only build ´energy-neutral´ buildings. The increase in Smart Buildings and technology in real estate is also of importance for the Facility …