Small RNAs are important regulators of genome function, yet their prediction in genomes is still a major computational challenge. Statistical analyses of pre-miRNA sequences indicated that their 2D structure tends to have a minimal free energy (MFE) significantly lower than MFE values of equivalently …

Background: Motor learning is central to domains such as sports and rehabilitation; however, often terminologies are insufficiently uniform to allow effective sharing of experience or translation of knowledge. A study using a Delphi technique was conducted to ascertain level of agreement between experts …

The effects of global ageing are mostly felt in the developing world. Older populations are experiencing extreme poverty and cope with financial difficulties that obstruct their access to public health and social care (Shah, 2011). Governments of emerging economies manage the multi pillar system that …

The nation-state had a long history of success, but today it is failing its citizens on a global scale. Over the last hundred years, nation-states focussed on maximizing internal unity and jurisdictional sovereignty. Benjamin R. Barber’s ‘If Mayors Ruled The World’ is the central source of this thesis …

The Mastication Observation and Evaluation (MOE) instrument was developed to allow objective assessment of a child's mastication process. It contains 14 items and was developed over three Delphi rounds. The present study concerns the further development of the MOE using the COSMIN (Consensus based Standard …

In this paper we present the design and field trial of the Dynamic Collage. The Dynamic Collage was designed to facilitate and to stimulate participation of family members in the informal care of an elderly person. The Dynamic Collage enabled relatives to update their current activity by sending a photo …

This research paper focuses on how the use of the internet can be a potential marketing tool for restaurants and local businesses such as bars and cafés. The goal of this research is to set up a consultancy company, specialized in proposing strategies for restaurants using online tools, to enable them …

Scanning tunneling microscopy is an important and enabling tool for condensed matter physics and surface science. The low temperature STM in Leiden (Prof. J. Van Ruitenbeek and Prof J. Aarts) is used for research in the field of atomic/molecular electronics and superconductivity. The current low temperature …

The Netherlands breeds higher segment, potential Olympics horses with unbelievably high price ranges. These horses are already being exported internationally. However, the export approach might lack efficiency. The following research question is brought forward to research whether this sector has potential …

The transatlantic data transfer between the U.S. and the EU would have been extremely complex and expensive if the European Commission together with the U.S. Department of Commerce had not originated the Safe Harbor agreement in 2000. As recently as the beginning of 2014 the European Parliament, especially …