An attempt was made to develop a method for the determination of volatile organic compounds (VOCs) in air by gas chromatography mass spectrometry (GC-MS) analysis and chemical sample desorption of the 3M 3500 passive diffusion sampler. The method included a complex mixture of 205 polar and non-polar …

Development of novel testing strategies to detect adverse human health effects is of interest to replace in vivo-based drug and chemical safety testing. The aim of the present study was to investigate whether physiologically based kinetic (PBK) modeling-facilitated conversion of in vitro toxicity data …

The interaction between physical drivers from oceanographic, hydrological, and meteorological processes in coastal areas can result in compound flooding. Compound flood events, like Cyclone Idai and Hurricane Harvey, have revealed the devastating consequences of the co-occurrence of coastal and river …

During this research project the influence of selenium enriched growing environment on the phenolic composition on several Allium species is studied. Besides this, the influence on morphological properties is also monitored. Folin-Ciocalteu method is used to determine the total phenolic content and High …

It can be concluded that the HBM4EU serum sample preparation method is suitable for Effect-Directed Analysis. The method allows a recovery of all bioactive compounds of interest from serum in the EDA products, with little loss of compounds: bioassay spectra and chromatograms. Nevertheless, the HBM4EU …

In the recent past, the use of resins in modern tread compounds has increased considerably, in order to further improve tire properties. Based on the experience with silica-silane filler system, which led to a different network structure and a significantly changed devulcanization behavior, the influence …

Tires are an important vehicle component, as car handling, safety and fuel economy depend for a major part on the tire composition and construction. As a consequence, tires are improved continuously. The most prominent improvement in the recent past was the use of a silica-silane filler system in passenger …

From the article: "To enable selection of novel chemicals for new processes, there is a recognized need for alternative toxicity screening assays to assess potential risks to man and the environment. For human health hazard assessment these screening assays need to be translational to humans, have …

Extrudate swell simulations and experiments have been performed with a viscoelastic tire rubber compound at high flow rates through a circular die. A 3-mode PTT model was fitted onto rheological data of the rubber. The PTT model covers the range of shear rates present in the simulation. Convergence of …

From PLoS website: In general, dietary antigens are tolerated by the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) by the environmental …