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Guidance for assessment of the inflammation etiologic criterion for the GLIM diagnosis of malnutrition: A modified Delphi approach

Cederholm, Tommy; Jensen, Gordon; Ballesteros-Pomar, Maria; Blaauw, Renee; Correia, Maria Isabel; Cuerda, Cristina; Evans, David; Fukushima, Ryoji; Ochoa Gautier, Juan; Gonzalez, Maria Cristina; van Gossum, Andre; Gramlich, Leah; Hartono, Josep; Heymsfield, Steven; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Jayatissa, Renuka; Keller, Heather; Malone, Ainsley; Manzanares, William; McMahon, M Molly; Mendez, Yolanda; Mogensen, Kris; Mori, Naoharu; Muscaritoli, Maurizio; Contreras Nogales, Guillermo; Nyulasi, Ibolya; Phillips, Wendy; Pirlich, Matthias; Pisprasert, Veeradej; Rothenberg, Elisabet; de van der Schueren, Marian; Ping Shi, Han; Steiber, Alison; Winkler, Marion; Barazzoni, Rocco; Compher, Charlene

Background & aims: The Global Leadership Initiative on Malnutrition (GLIM) approach to malnutrition diagnosis is based on assessment of three phenotypic (weight loss, low body mass index, and reduced skeletal muscle mass) and two etiologic (reduced food intake/assimilation and disease burden/inflammation) …

2024-05-01AlgemeenArtikel

Guidance for assessment of the inflammation etiologic criterion for the GLIM diagnosis of malnutrition: A modified Delphi approach

Jensen, Gordon; Cederholm, Tommy; Ballesteros-Pomar, Maria; Blaauw, Renee; Correia, Maria Isabel; Cuerda, Cristina; Evans, David; Fukushima, Ryoji; Ochoa Gautier, Juan; Gonzalez, Maria Cristina; van Gossum, Andre; Gramlich, Leah; Hartono, Josep; Heymsfield, Steven; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Jayatissa, Renuka; Keller, Heather; Malone, Ainsley; Manzanares, William; McMahon, M Molly; Mendez, Yolanda; Mogensen, Kris; Mori, Naoharu; Muscaritoli, Maurizio; Contreras Nogales, Guillermo; Nyulasi, Ibolya; Phillips, Wendy; Pirlich, Matthias; Pisprasert, Veeradej; Rothenberg, Elisabet; de van der Schueren, Marian; Ping Shi, Han; Steiber, Alison; Winkler, Marion; Compher, Charlene; Barazzoni, Rocco

Background: The Global Leadership Initiative on Malnutrition (GLIM) approach to malnutrition diagnosis is based on assessment of three phenotypic (weight loss, low body mass index, and reduced skeletal muscle mass) and two etiologic (reduced food intake/assimilation and disease burden/inflammation) criteria, …

2024-01-15AlgemeenArtikel

Transitie van zorg bij adolescente inflammatory bowel disease (IBD) patiënten

Dimphy Slot (Student)

Doel van deze studie was inzicht krijgen in de huidige adolescenten-patiëntenpopulatie met M.Crohn (CD) en Colitis Ulcerosa (UC) van diagnose (vanaf 1-1-2005) tot één jaar na transitie, van Kindergeneeskunde naar de volwassen MDL-zorg binnen het Zuyderland Medisch Centrum. Hiermee beogen we een bijdragen …

2024GezondheidMaster

Sulforaphane as a potential modifier of calorie-induced inflammation

Steenwijk, H.P. van; Vinken, A.; Osch, F. van; Peppelenbos, H. (Lector); Troost, F.J.; Bast, A.; Semen, K.O.; Boer, A. de

Background and aims: Observational data indicate that diets rich in fruits and vegetables have a positive effect on inflammatory status, improve metabolic resilience and may protect against the development of non-communicable diseases. Nevertheless, experimental evidence demonstrating a causal relationship …

2023-11-28Mens & MaatschappijArtikel

Mirror meetings as a tool to enhance professionals' awareness of the lived experiences of young people with inflammatory bowel disease

J.N.T. Sattoe; H.J.M. van Heijningen-Tousain; A.L. van Staa

During mirror meetings, professionals were confronted with the experiences of young people (YP) with inflammatory bowel disease to encourage them to improve their transitional care arrangements. The mirror meetings were held under guidance of an independent moderator. YP conversed about their transition …

2023-08-30GezondheidArtikel

Sex differences in the association between dual-energy x-ray absorptiometry-measured body composition and periodontitis

Zhu, Peijun; Li, An; Cai, Qingqing; Chen, Yuntao; Liu, Yang; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Tjakkes, Geerten-Has; Xu, Shulan

Background: A positive association between obesity based on body mass index (BMI) and periodontitis has been reported. Fat tissue-related systemic inflammation acts as the link to periodontal comorbidities of obesity. However, the BMI is unable to distinguish fat and fat-free tissues. More precise measures …

2023-08-28AlgemeenArtikel

The TNFR1 antagonist Atrosimab reduces neuronal loss, glial activation and memory deficits in an acute mouse model of neurodegeneration

Ortí-Casañ, N.; Boerema, A.S. (Lid Lectoraat); Köpke, K.; Ebskamp, A.; Keijser, J.; Zhang, Y.; Chen, T.; Dolga, A.M.; Broersen, K.; Fischer, R.; Pfizenmaier, K.; Kontermann, R.E.; Eisel, U.L.M.

Tumor necrosis factor alpha (TNF-α) and its key role in modulating immune responses has been widely recognized as a therapeutic target for inflammatory and neurodegenerative diseases. Even though inhibition of TNF-α is beneficial for the treatment of certain inflammatory diseases, total neutralization …

2023-06-30GezondheidArtikel

Obesity-induced TET2 disfunction in DNMT3A mutated haematopoietic cells increases myelopoiesis, resulting in increased risk for cardiovascular disease development

Arina Kochetkova (Student)

Clonal haematopoiesis of intermediate potential (CHIP) driven by somatic mutations in DNMT3A and TET2 has been recently recognized as a new risk factor for cardiovascular diseases (CVD). The haematopoietic clones with mutations in these genes are frequently found in myeloid malignancies and according …

2023-06-13Gezondheid; …Bachelor

Targeting Sphingolipid Metabolism in Atherosclerosis

Willem Tielemans Zamora (Student)

Cardiovascular diseases (CVDs) are by far the leading cause of death due to non communicable diseases in the world. The development of CVDs in many cases is caused by atherosclerosis. In atherosclerosis, plaques in blood vessels are formed by the excessive accumulation of lipids in the endothelial lining. …

2023-05-31Gezondheid; …Bachelor

Effects of Exercise during Chemo- or Radiotherapy on Immune Markers

Anne de Hoop (Onderzoeker); Karin Valkenet (Onderzoeker); Jaap Dronkers (Onderzoeker); Cyrille Krul (Lector); Jelle Ruurda (Onderzoeker); Cindy Veenhof (Lector); Raymond Pieters (Lector)

Introduction: Patients with cancer receiving radio- or chemotherapy undergo many immunological stressors. Chronic regular exercise has been shown to positively influence the immune system in several populations, while exercise overload may have negative effects. Exercise is currently recommended for …

2023GezondheidArtikel

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